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Home - Products - Immunology/Inflammation - Lipoxygenase - BW 755C

BW 755C

CAS No. 66000-40-6

BW 755C( —— )

Catalog No. M27503 CAS No. 66000-40-6

BW 755C is a dual inhibitor of 5-lipoxygenase (5-LO) and cyclooxygenase (COX) pathways.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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5MG 53 Get Quote
10MG 71 Get Quote
25MG 111 Get Quote
50MG 158 Get Quote
100MG 231 Get Quote
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Biological Information

  • Product Name
    BW 755C
  • Note
    Research use only, not for human use.
  • Brief Description
    BW 755C is a dual inhibitor of 5-lipoxygenase (5-LO) and cyclooxygenase (COX) pathways.
  • Description
    BW 755C is a dual inhibitor of 5-lipoxygenase (5-LO) and cyclooxygenase (COX) pathways.(In Vitro):BW 755C is approximately equipotent inhibitors of COX-1 and COX-2 in intact cells.
  • In Vitro
    ——
  • In Vivo
    Animal Model:Immature Wistar rats ~22 days of age Dosage:0.03, 0.1, 0.3, 1.0, 3.1 and 10 mg/rat Administration:Subcutaneous injection, once Result:Reduced 5-HETE (moderately) and 12-HETE (strongly).
  • Synonyms
    ——
  • Pathway
    Immunology/Inflammation
  • Target
    Lipoxygenase
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    66000-40-6
  • Formula Weight
    229.2
  • Molecular Formula
    C10H10F3N3
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (436.30 mM)
  • SMILES
    NC(CC1)=NN1c1cccc(C(F)(F)F)c1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Chao W, et al. Inotilone from Inonotus linteus suppresses lung cancer metastasis in vitro and in vivo through ROS-mediated PI3K/AKT/MAPK signaling pathways. Sci Rep. 2019 Feb 20;9(1):2344.
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